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We conclude with a discussion of the knowledge gaps that must be addressed before incretin-based therapies can be properly deployed for maximum benefit in the treatment of obesity and T2DM

Patients who inject more frequently than weekly report higher rates of GI adverse events, particularly nausea and vomiting

Gastrointestinal side effects such as nausea, vomiting, diarrhea, or constipation are common across GLP-1 therapies

Vitamin B12 GLP-1 agonists can sometimes interfere with the absorption of vitamin B-12 in the gastrointestinal tract, potentially leading to lower levels of this essential nutrient over time

It's nice that light or air can never be added with this type of packaging, because vit C is sensitive to that

In SUSTAIN-6, wherein semaglutide (subcutaneous injection) was administered at 0.5 or 1 mg per week, MACE was also reduced by 26% in the semaglutide group compared with the placebo group (HR 0.74, 95% CI 0.580.95) as was stroke (HR 0.61, 95% CI 0.380.99) [17]