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Gastric emptying is delayed and appetite centres in the hypothalamus are modulated, contributing to weight loss and improved glycaemic control

placebo: 9.2%) and constipation (tirzepatide: 23.0%

Lhcgr mRNA levels of 50 g/L (0.15 IU/L) rhGH-treated LCs were significantly lower than those of controls

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Tell patients to look out for increasing redness, warmth, or drainage from the injection sites and contact their healthcare provider immediately if they notice these signs

Better blood pressure management 41% of patients in the 8 mg groups and 30% in the 12 mg group were able to stop taking at least one antihypertensive medication after 48 weeks on retatrutide