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Tirzepatide fails to limit MC38 tumor growth or improve CD8+ T cell response in lean mice Since the anticancer effects of tirzepatide require CD8+ T cells but not direct receptor engagement on either tumor or CD8+ T cells, we explored the possibility that reversing obesity-associated metabolic dysfunction is key to the inhibitory effect of tirzepatide on obesity-stimulated MC38 tumor growth
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Managing vomiting requires dose reduction, slower titration, dietary modifications, and occasionally antiemetic medications
Hydration: GLP-1s and thyroid health both rely on good hydration
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