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Although direct neo-N-terminal fragments of caspase-1 were not enriched in the TMT-TAILS dataset, potentially due to labeling inefficiencies, we observed significant depletion of peptides spanning the X(PC) cleavage site in the active protease-treated samples, providing strong evidence of on-target cleavage (Extended Data Fig
Bone density and strength: GH and IGF-1 stimulate osteoblasts increasing bone formation
Dose-dependent reductions in testosterone and sperm density were documented, with partial recovery after drug discontinuation in several models
Ibuprofen is frequently detected in water systems due to its widespread use and improper disposal (Austin et al., 2022
