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It was observed that urate uptake by Urat1 exhibited Cl dependency, with an approximately 57% increase in Km value
Patients wanting to enhance their metabolism or lose weight
Its role in improving insulin signaling and promoting glucose uptake reduces the deleterious effects of insulin resistance
Further 2025 reviews highlight its safety and efficacy in improving insulin sensitivity in overweight, insulin-resistant cohorts (439)
doi:10.1152/physrev.1998.78.2.393
10.1016/S0140-6736(71)92415-9
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