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Ryter SW, Kim HP, Hoetzel A, Park JW, Nakahira K, Wang X et al

Dysfunction of system Xc - depletes GSH, further compromising the cells ability to counteract oxidative damage ( Iron metabolism is another critical factor in ferroptosis

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pylori activity

Platelets form aggregates with infected red blood cells via CD36 and with leukocytes via the CD40-CD40L pair, promoting vascular sequestration of red blood cells and immunothrombosis in the microcirculation, particularly in the cerebral microcirculation

This unique physiological characteristic of cancer cells needs enough nutrition supply to support their survival and proliferation (Zhang et al., 2020b)