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Phone support routes through an AI with roughly 19-minute wait times, and email responses take 2472 hours, sometimes without fully addressing the question on the first try
The most prevalent and clinically validated strategy utilizes enzymatically cleavable linkers, which leverage the high activity of specific lysosomal proteases (e.g., cathepsin B)
The key: co-formulation with an absorption enhancer (SNAC) creating a localized pH window in the stomach, transiently protecting the molecule during passage
This can cost more than they consider worth spending
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