More importantly, studies have consistently shown that vitamin B12 deficiencies are linked to obesity and insulin resistance
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[41] [42] Functional vitamin B 12 deficiency can also develop with heavy regular use of nitrous oxide N 2 O, also known as "laughing gas", by oxidizing the cobalt atom and inactivating the vitamin
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Further, as Healthline points out, injectable B12 which is generally given in much higher dosages than what can be found in food and multivitamins has been associated with more commonplace side effects, minor as they may be