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Patients with family history of these more common thyroid cancers are not automatically excluded from GLP-1 therapy based on this specific contraindication

In clinical trials, some participants experienced improvements in their blood sugar levels within the first few weeks of taking tirzepatide

doi: 10.1111/j.1432-1033.1993.tb17986.x 51 KiefferTJMcIntoshCHPedersonRA

Epub 2011 May 31

For people with chronic obesity and cardiovascular complications, GLP-1 receptor agonists are preferred to amphetamine-based therapies like phentermine, which can worsen blood pressure, heart rate, anxiety, and insomnia