Protein is non-negotiable GLP-1 agonists cause weight loss through multiple mechanisms, but not all weight loss is equal
GLP-1 receptor agonists and GLP-1 and glucose-dependent insulinotropic peptide agonists have several mechanisms of action, including reduction of gastric emptying, inhibition of glucagon secretion, beneficial changes in the intestinal microbiome, and direct effects on hypothalamic nuclei to enhance satiety (which promotes weight loss)
The trade-off is co-stimulation of cortisol and prolactin that ipamorelin largely avoids
The appetite suppression means less mental energy spent thinking about, resisting, or planning around food
If your insurance plan denies coverage, we will recommend self-pay options: Zepbound from Lilly Direct: $349/month for 2.5mg dose $499/month for 5.0mg (and higher doses when refilled within 45 days) Medication is sent in vials along with syringes/supplies Wegovy from NovoCare: $499/month (any dose) Medication is an autoinjector (no syringes/needles needed) You may use your insurance for follow up medical visits with your provider (or self-pay $100)
Keep electrolytes balanced: Tirzepatide-related GI symptoms can affect mineral absorption
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