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Notably, glutamine was required for the production of N2--GluGln, so the elevation of this metabolite indicated the increased abundance of glutamine in APAP_BSL group

SKOV3 cells were administered with clinically relevant anesthetic concentrations of 2.5% sevoflurane (ABOTT, Sittingbourne, UK) and 4 g/mL propofol (Sigma-Aldrich, Dorset, UK), or media (nave control), or intralipid (vehicle control) (Santa Cruz Biotechnology, Dallas, Texas, USA) for 2 h and followed by 24-h recovery in fresh media

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However, this equilibrium is based on high concentrations of CO