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That selectivity matters in research for two reasons: Cleaner interpretation: If a compound pushes fewer off-target endocrine pathways, observed outcomes are easier to connect to the intended mechanism
This means discerning customers can get maximum value for their money and they wont be tied to just one or two mediocre products
A randomized double-blind, placebo-controlled, phase 3 trial revealed that participants taking naltrexone-bupropion combinations lost significantly more weight than those on placebo
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