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However, the body weight of 5A-1MQ-treated obese mice (WD/LD-T group), which was indistinguishable from the other DIO groups at study start, was indistinguishable from the lean control (LD/LD-V) group at study completion (results with FDR correction
doi:10.1001/jama.2013.280490
peripheral vascular thrombosis Hematological : Polycythemia vera (a rare type of blood cancer) Gastrointestinal : Mild, transient diarrhea Dermatological : Itching
In aged rodents, the same pharmacology has been extended to skeletal-muscle pathology, where it preserves muscle stem cell function and mitigates sarcopenia [3]
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