Semaglutide treatment in our case series of patients with PWS without diabetes led to weight reduction and/or weight maintenance, as well as to appetite suppression as reported by patients and caregivers
Similarly, analyses of secondary cognitive and functional outcomes did not reveal meaningful differences between treatment and placebo groups, indicating no clinically significant benefit in cognition or daily functioning over the primary treatment period
Glucagon signalling, classically associated with raising blood glucose, also stimulates lipolysis in adipose tissue, increases mitochondrial activity in hepatocytes, and promotes whole-body energy expenditure
Im in the lowest dose and I have had zero side effects
Labs showed mild hypokalemia, elevated hematocrit, and elevated albumin and total protein, suggesting a depleted volume status likely secondary to protracted vomiting
After the patent issue, he tried to interest when large diabetes drug company, but all the company rejected his opportunity