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For extremely sensitive, long-term liquid storage, some labs will displace the oxygen in the headspace of the vial with an inert gas like argon or nitrogen before sealing and freezing
However, their low bioavailability and off-target effects limit their clinical application
Moreover, they contain additional substances that are toxic to humans
(1995b)
Some may experience mild digestive changes initially taking it with meals can help
It is taken up by the PepT1 transporter, which is upregulated in inflamed gut tissue, making it interesting for inflammatory bowel disease
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