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Any treatment plan involving these agents should include: Regular blood tests (glucose, HbA1c, IGF-1, lipids, liver function, renal function) Documented informed consent regarding off-label or investigational use Dietitian input to monitor nutritional status, particularly during periods of rapid weight loss or reduced appetite Reconciliation of all concomitant medicines , including over-the-counter products and supplements, to minimise interaction risks Clear escalation pathways if side effects arise, including urgent review for severe abdominal pain, dehydration, or hypoglycaemia Ongoing review by a named responsible clinician Reporting of any suspected adverse effects via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk) Your health and safety are best protected by working transparently within the NHS or a regulated private medical setting, with full disclosure of all medicines prescribed or otherwise that you are taking

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When cell turnover slows with age or when dead cells build up on the surface, the complexion can look dull, regardless of pigment levels

Supports the regeneration and repair of tissue Promotes a healthy gut Supports joint and bone health Promotes a healthy response to inflammation Manufactured in a GMP Certified Facility Manufactured in an FDA inspected facility Adults: As a dietary supplement, take one to two capsules per day

Nutrients (2023) 15:743