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Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

Those aren't theoretical differences

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5 g/day improved erectile function in 31% of men with abnormal nitric oxide markers, versus 12% on placebo

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Additional studies in multiple dystrophic mouse models have confirmed IGF-1 analog benefits in improving muscle function and reducing pathological features