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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

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This regulation is bidirectional: the peptide can increase or decrease NO production depending on the pathological context, thereby contributing to vascular protection and inflammation reduction

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Lot-Linked COAs : Each vials lot number ties directly to third-party HPLC/MS results

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