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In support of this, we prepared primary cultures of cerebellar granule cells from Bdnf-Luc mice using a 96-well culture plate, and found that membrane depolarization increased luciferase activity, which agreed with previous reports regarding the activity-dependent Bdnf expression in cultured cerebellar granule cells 32,33

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The GHK part consists of the three amino acids, classifying them as short-chain peptides, which are categorized by the number of amino acids they contain

Chinese Academy of Medical Science Innovation Fund for Medical Sciences grants no

This gives the body more time to adjust to the medicine

The addition of the acetyl group also endows acetyl L-carnitine (ALC) with a greater solubility in water, which enables it not only to diffuse easily across the inner wall of the mitochondria and into the cell cytosol, but also cross cell membranes in general more easily