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Medical Product Alert N2/2024: Falsified OZEMPIC (semaglutide)

Effective weight loss typically begins at maintenance doses (1 mg or higher)

However, it is unclear whether the polymorphism of MTHFR could be an independent or an add-on risk factor for specific psychiatric symptoms, such as anxiety, depression, positive, or negative symptoms of schizophrenia, or acts as risk factor for specific psychiatric disorders, such as schizophrenia, major depression, autisms, and bipolar disorders

I tell more of that story in my Camp Shame podcasts (here and here)

Naltrexone/Bupropion: Approved for long-term use but requires monitoring for potential side effects

The data sheets of both drugs indicate that they can be used in patients with mild or moderate renal failure, adjusting the dose and carefully monitoring renal function