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Neuroinflammation induced by TNF- can affect the signaling of neurotrophins such as NGF and BDNF, which are essential for neuronal survival, growth, and plasticity (Saghazadeh and Rezaei 2017)
DOI: 10.1038/s41598-024-66034-9
Furthermore, leaf metabolism seems to be very different from root metabolism
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However, this practice inevitably narrows the clinical spectrum represented in research samples and reduces natural heterogeneity of ASD, limiting the generalizability of findings
Pro-inflammatory cytokine production starts decreasing at the cellular level (Dalmasso et al., 2008)
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