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Alkylating agents such as NEM or iodoacetamide can be added to block free thiols and lock the GSH/GSSG ratio at the time of collection

Further, LAT1-dependent binding affinity was measured and calculated with or without the presence of the LAT1 inhibitor, 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH)

Adeoye, O., Olawumi, J., Opeyemi, A., & Christiania, O

M.AggarwalA

A recent retrospective clinical study evaluated NAC's ability to act as a therapeutic agent against the microvascular inflammation that drives profound fatigue in post-viral syndromes