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NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site

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Annu Rev Plant Biol 52:407436 Shen S, Peng M, Fang H, Wang Z, Zhou S, Jing X, Zhang M, Yang C, Guo H, Li Y, Lei L, Shi Y, Sun Y, Liu X, Xu C, Tohge T, Yuan M, Fernie AR, Ning Y, Wang GL, Luo J (2021) An oryza-specific hydroxycinnamoyl tyramine gene cluster contributes to enhanced disease resistance

Oral therapies, scalable manufacturing, lower-cost supply chains, and simplified distribution could expand GLP-1 adoption outside the highest-income markets

You may, at least for now, be able to find generic tirzepatide for about $299 monthlybut producing generics is a legal gray area, and this option may not be around much longer

For biopharma leaders, the critical question is whether to lead, adapt, or play catch-up