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Rare but serious risks include pancreatitis, gallbladder issues, and a theoretical risk of thyroid C-cell tumors based on animal studies
Physiol Rev 87: 1409-1439, 2007
L-Carnitine has antioxidant properties and reduces glutathione by reducing thiol groups [33]
2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation
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