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Research note: The mechanistic descriptions above are derived from published preclinical and Phase II clinical research data

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In lymphocyte-deficient mice (T and B cells), the number of activated microglia was significantly reduced after ischemic stroke, particularly in the ischemic border zone (95)

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This difference in effectiveness makes the case for tirzepatide-based development projects very strong for pharmaceutical makers and CRO/CDMO companies that are looking at peptide APIs for anti-inflammatory uses

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