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Waltham, MA: Academic Press, Elsevier

In these cases, the perforations leak pus and stool out of the colon into the abdominal cavity, a condition called peritonitis

Therapeutic interventions aimed at modulating lipid availability, such as ACAT inhibitors, PPAR antagonists, or scavenger-receptor blockade, can reduce the supply of anti-ferroptotic lipid mediators and promote oxidative lipid stress within tumor cells