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The most common side effects include: Nausea One of the most frequently reported side effects Often mild to moderate Usually improves over time or with dose adjustment Diarrhea Loose stools or increased bowel movements Staying hydrated is important Decreased Appetite May contribute to weight loss Can sometimes lead to eating too littlemonitor your calorie and nutrient intake Vomiting Less common than nausea, but can occur especially at higher doses Talk to your provider if persistent or severe Constipation May occur as digestion slows down Drinking water and adding fiber can help Indigestion or Heartburn Also known as dyspepsia Eating smaller meals and avoiding spicy foods may reduce discomfort Fatigue Some users report feeling tired, especially during the first few weeks Less Common but Serious Side Effects Although rare, some patients may experience more serious side effects

Clinical Update 3/17/2021 Does Coffee Consumption Lower Cardiovascular Risk, or Is It the Other Way Around

To our knowledge, this is the first study to examine weight loss in patients with overweight or obesity who are living with diabetes and prescribed GLP-1 agonists in the real world

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