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Vildagliptin has been approved for use by the European Medicines Agency (EMA), but has not been approved for use in the US by the US FDA

Ozempic, while slower in weight reduction, offers sustained benefits and is often preferred due to its dual role in managing blood sugar and promoting gradual weight loss

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The mechanisms behind gallstone formation with GLP-1 agonists involve rapid weight loss and altered bile composition, both of which may be less pronounced at microdoses where weight loss is slower