You may experience fatigue or lethargy, among other symptoms, if you have a B12 deficiency
If levels of oxalate in the glomerular filtrate increase (hyperoxaluria) it can chelate Ca 2+ ions forming the insoluble compound, calcium oxalate
And before we get into it, I do want to mention something a little bit new that I haven't talked about much lately, and that is a brand new podcast we launched called Nutrition Science Daily
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Side effects during the first week at 1.0 mg can be more noticeable than previous increases