Discrepancies in patient characteristics, including renal function, between these groups were minimized after PSM
1 In the Surpass-Early trial, nearly 800 adults diagnosed with type 2 diabetes within the past four years were assigned to add either tirzepatide, sold as 1 Most patients in the control group received other GLP-1 drugs including semaglutide, sold by Novo Nordisk as Ozempic and Rybelsus, or Lilly's own dulaglutide
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These social determinants of health create additional complexity in treatment implementation, particularly in underserved populations where obesity prevalence is often highest
Lancet 394:131138 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
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