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Common side effects of Semaglutide include nausea, diarrhea, vomiting, constipation, and abdominal pain
GLP-1 receptors are found in brain regions associated with reward and pleasure, so by modulating these pathways, semaglutide and tirzepatide may influence the rewarding aspects of food consumption
Padman, B
GLP-1RA additionally act at the central nervous system level, increasing satiety leading to weight loss 30 - 32
Despite the expanding use of anti-obesity medications (AOMs), sarcopenia and sarcopenic obesity (SO) remain major concerns in this population
She reports consultancy fees from AstraZeneca, Boehringer Ingelheim, Bayer, Eli Lilly, Novo Nordisk, Travere Therapeutics Inc, ProKidney and Alnylam
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