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In addition, elevated TMAO levels are closely associated with an increased risk of cardiovascular disease in CKD patients, possibly due to TMAO enhancing platelet reactivity and amplifying endothelial inflammatory responses, thereby increasing the risk of thrombosis

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3.1 Diabetic nephropathy Globally, approximately 40% of individuals with diabetes are at risk of developing CKD, revealing a close association between these two conditions

J Autoimmun (2017) 83:95112

This supports the use of avocado as a smart raw food for antioxidant support