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The NHS advises that taking up to 2mg (2000 micrograms) daily of vitamin B12 supplements is unlikely to cause harm, with no established upper limit in the UK

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Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency

Knowing when to reduce dose or discontinue Not every side effect requires discontinuation, but some warrant reducing dose or stopping use

B12 injections are intended to restore optimal levels of this important vitamin to alleviate symptoms of deficiency

Anxiety and jitters : Common with stimulant use