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A successful program should improve metabolic health, reduce excess body fat, preserve strength and lean tissue, and create results that can be maintained over time

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This is rare but can occur with sertraline, particularly when combined with other serotonergic medications (e.g., other antidepressants, tramadol, triptans, St John's wort, or certain illicit drugs) In an emergency: Call 999 if you experience severe chest or abdominal pain, signs of a severe allergic reaction, severe confusion, high fever, or seizures Contact NHS 111 for urgent but non-emergency advice when your GP is unavailable Before starting any new medication (prescription, over-the-counter, or herbal), inform your pharmacist that you are taking both Mounjaro and sertraline