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Patients could expect to pay over $14,000 a year out-of-pocket, whereas compounded medications can be cheaper
First-line treatment typically involves: Methotrexate the most commonly prescribed conventional synthetic DMARD Sulfasalazine or hydroxychloroquine alternative or combination options Leflunomide for patients who cannot tolerate methotrexate These medications are usually combined with short-term corticosteroids (such as prednisolone) to provide rapid symptom relief whilst DMARDs take effect, which can take several weeks to months
Hypertension in adults: diagnosis and management (NG136) Visual summary
Patients might return for a follow-up visit to determine whether more treatments are needed or to discuss their results further
Patients should inform their healthcare provider about all medications, supplements, and over-the-counter products they use, as drug interactions or cumulative effects may impact liver function
No conclusions can be made for efficacy or safety outcomes beyond glycemic reduction and weight loss since these outcomes were not evaluated
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