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This has been replicated in animal models using both tacrolimus and CsA with adverse remodeling features of vascular stiffness, thickening, inflammation and fibrosis noted in treated animals (159, 160)

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If cramps are becoming a regular part of your GLP-1 experience, bring it up at your next appointment

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This includes creating a relaxing bedtime routine, optimizing your sleep environment by minimizing noise and light disruptions, and establishing a consistent sleep schedule