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A part of one study is presented by Braunstein et al
Ren S, Xu Y, Dong X, Mu Q, Chen X, Yu Y, et al
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With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
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