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Over time, plaques can narrow the arteries or become unstable

Free radicals generated from UV exposure, pollution, and heat damage skin cells and accelerate aging

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Investigative efforts so far concerning enterotypes, such as alpha diversity, the Firmicutes-to-Bacteroidetes ratio, aim at the identification of an MDD-specific fecal signature (Valles-Colomer et al., 2019)

OA primarily manifests as joint pain, dysfunction, and deformity, most often impacting load-bearing joints such as the knee and hip