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Despite the profound impact of fibrosis, approved therapeutics that specifically target this pathology are limited
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Other medications including: Environmental toxins Toxins in the environment like pollutants and pesticides can lead to increased intestinal permeability: Pollutants like pesticides, heavy metals, and industrial-grade chemicals can lead to toxicity in the gastrointestinal tract, damaging the intestinal lining and causing a leaky gut
then, they treated the DM rats with intraperitoneal injection of exendin-4 at 1 nmol/kg for 24 weeks (49)
This is typically short-lived and should subside within a few hours after the injection
Presented for research literature review only Chaudhry A et al
