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A recent trial from the drugmaker Eli Lilly involving adults with overweight or obesity plus one weight-related comorbidity found that retatrutide led to an average weight loss of 28 percent body weight after 80 weeks on the highest dose

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Feb 2017;31:70-78

Examining the risk of depression or self-harm associated with incretin-based therapies used to manage hyperglycaemia in patients with type 2 diabetes: a Cohort Study using the UK Clinical Practice Research Datalink