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Lifestyle interventions including adequate protein intake, resistance exercise, sleep optimisation, and alcohol reduction are evidence-based complements to weight-loss pharmacotherapy

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The expression profile of genes monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor (TNF), tumor necrosis factor receptor type 1 (TNFR1), transforming growth factor-beta-1 (TGF1), collagen type I alpha 1 chain (Col1,) actin alpha 2 smooth muscle (SMA), tissue inhibitor of metalloproteinases 1 (Timp1), and haptoglobin (Hp) associated with non-alcoholic fatty liver disease (NAFLD) were elevated in the livers of mice fed an HFD for 16 weeks compared with those from mice fed the control diet (Fig

The most common side effects include: Wegovy may also cause hypoglycemia (low blood sugar) when used with some other anti-diabetic drugs