Philip Pape: 4:41 The most intriguing of those is the ability to stimulate GLP-1, which is the same hormone targeted by the weight loss medications like Gozembek and Manjaro
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In a phase 3, double-blind, randomized, controlled trial, 2,539 adults with a body-mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related complication, were given weekly subcutaneous injections of tirzepatide (5 mg, 10 mg, or 15 mg) or a placebo for 72 weeks
Tirzepatide (Mounjaro) Tirzepatide (Mounjaro) Mechanism of Action: Tirzepatide is a dual agonist of GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors
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They work by mimicking a glucagon-like peptide-1, a natural hormone in your body that helps regulate appetite, digestion, and insulin release