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Zeissig S, Brgel N, Gnzel D, Richter J, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD: Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

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Patients on the 12mg weekly dose lost an average of 24.2% of body weight over 48 weeks

By stimulating repair pathways, GHK-Cu aims to prolong and deepen the rejuvenating effects of such procedures