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54 Cancer stem cell (CSC)-like traits, characterized by robust DNA repair capacity and increased expression of drug efflux pumps, are tightly linked to chemoresistant phenotypes

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These pain-relieving effects are blocked by drugs that affect norepinephrine, but not serotonin, suggesting that the pain relief works through adrenergic pathways (9)

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Regulatory feedback mechanisms leading to an increase in the dietary absorption of LC, and/or de novo synthesis may take place to overcome the LC deficiency and reduce the loss by urinary excretion

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