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Potential of TMAO as a Therapeutic Target in AS Several therapeutic strategies to lower TMAO levels that are currently being explored are summarized below ( Figure 2 )
368,369,370 HSF2 and DLG2 can block the oligomerization of ASC by interfering with the interaction between ASC and NLRP3, thereby inhibiting the activation of the NLRP3 inflammasome and the upregulation of IL-1 expression and alleviating the inflammatory response
Dietary modifications play a crucial role in managing symptoms
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