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Using next-generation RNA-seq sequencing technology, they confirmed that GHK-Cu modulates the expression of 4,231 genes , of which 2,861 are upregulated and 1,370 are downregulated

doi: 10.1038/s41598-020-70248-y 339 WesselsA

Further mechanistic studies revealed that LPS downregulates UFL1 expression, activates p53/SLC7A11 system, and modulates autophagy, thereby inducing ferroptosis (60)

In practical terms, the difference is small enough that standard dosing protocols do not adjust for it

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The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health