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Risks of Untreated Constipation While constipation might seem like a minor inconvenience, untreated or chronic constipation can lead to more serious health issues, including: Bowel Obstruction: Chronic constipation can cause a blockage in your intestines, leading to painful and potentially dangerous conditions

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Recently, a genetic screen revealed two lipid metabolism regulatorslysophosphatidylcholine acyltransferase 3 (LPCAT3) and acyl-CoA synthetase long-chain family member 4 (ACSL4)that drive ferroptosis via an accumulation of oxidized phospholipids in the cell membrane [40]