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These trials include more than 2,050 participants across diverse regions, and the first major results from TRANSCEND-T2D-1 are expected to be presented at the American Diabetes Association Scientific Sessions in June, then published in a peer-reviewed journal

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Preclinical work commonly screens low-micromolar ranges (e.g., 130 M) for pathway readouts such as 1-MNA reduction and lipogenesis suppression

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