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This affects cell replication resulting in aging
Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity
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10.1016/S0006-2952(02)01172-3 Biochem
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The best MOI value equals to 5 via the calculation of fluorescence microscope images as well as the evaluation of cell vitality (Fig
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