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Estradiol is converted reversibly to estrone, and both can be converted to estriol, which is a major urinary metabolite
In terms of safety, the overall rate of adverse events was highest with semaglutide 2.4 mg, followed by liraglutide 3.0 mg, liraglutide 1.8 mg, and semaglutide 1.0m g, compared to placebo
Similar in chemical structure to the GLP-1 produced in the body, it was originally approved by the FDA as Ozempic, an injectable diabetes treatment
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